Premium
Thalamic‐Caudal Zona Incerta Deep Brain Stimulation for Refractory Orthostatic Tremor: A Report of 3 Cases
Author(s) -
Athauda Dilan,
Georgiev Dejan,
AvilesOlmos Iciar,
Peters Amy,
Day Brian,
Brown Peter,
Zrinzo Ludvic,
Hariz Marwan,
Limousin Patricia,
Foltynie Thomas
Publication year - 2016
Publication title -
movement disorders clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 18
ISSN - 2330-1619
DOI - 10.1002/mdc3.12345
Subject(s) - zona incerta , deep brain stimulation , thalamus , medicine , essential tremor , neuroscience , psychology , movement disorders , physical medicine and rehabilitation , parkinson's disease , disease
Orthostatic tremor ( OT ) is a rare, disabling movement disorder characterized by the development of a high‐frequency tremor of the lower limbs and feelings of unsteadiness upon standing, which compel the patient to sit down or walk. Medical therapy is often unsatisfactory. Previous reports suggest that deep brain stimulation of the ventral intermediate nucleus of the thalamus may improve clinical outcomes. The authors report 3 patients who had intractable orthostatic tremor treated with bilateral deep brain stimulation of the ventral intermediate nucleus of the thalamus‐caudal zona incerta, resulting in improved and sustained clinical improvements in symptoms, although there were no apparent changes in the underlying tremor frequency or onset.