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Multifocal Motor Neuropathy Presenting as Pseudodystonia
Author(s) -
Garg Nidhi,
Heard Robert N.S.,
Kiers Lynette,
Gerraty Richard,
Yiannikas Con
Publication year - 2016
Publication title -
movement disorders clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 18
ISSN - 2330-1619
DOI - 10.1002/mdc3.12336
Subject(s) - multifocal motor neuropathy , mismatch negativity , medicine , weakness , neuroscience , presentation (obstetrics) , clinical neurophysiology , electromyography , physical medicine and rehabilitation , psychology , electroencephalography , surgery
View Supplementary Video 1 View Supplementary Video 2 Multifocal motor neuropathy (MMN) is an immune‐mediated neuropathy. Wasting and weakness typically dominate the clinical presentation. We describe four cases presenting with prominent cramping resembling a primary movement disorder. All cases had features of focal motor conduction block on neurophysiological studies. The involuntary movements resolved in all four patients following treatment with intravenous immunoglobulin. The presented cases highlight an unusual presentation of MMN and emphasize that peripheral nerve pathology can present with movement disorders mimicking central nervous system disease. Furthermore, the movement disorder appears particularly sensitive to standard therapy.