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Clinical Heterogeneity in Cerebral Hemiatrophy Syndromes
Author(s) -
Reiter Eva,
Heim Beatrice,
Scherfler Christoph,
Mueller Christoph,
Nocker Michael,
Ndayisaba JeanPierre,
Loescher Wolfgang,
Seppi Klaus,
Lees Andrew J.,
Warner Thomas,
Poewe Werner,
Wenning Gregor K.,
Djamshidian Atbin
Publication year - 2016
Publication title -
movement disorders clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 18
ISSN - 2330-1619
DOI - 10.1002/mdc3.12301
Subject(s) - irritability , parkinsonism , dystonia , medicine , pediatrics , movement disorders , mood disorders , etiology , psychiatry , cognition , anxiety , disease , pathology
Background Cerebral hemiatrophy syndromes can present with variable neurological symptoms. In childhood epilepsy, mental retardation and neuropsychiatric disorders are common while in adults movement disorders, such as highly asymmetric parkinsonism or hemidystonia as well as neuropsychiatric problems have been reported. Methods Here, we present three adult patients with features that expand the clinical spectrum and give an overview of the most common clinical signs associated with this rare condition. Results All three patients had prominent neuropsychiatric symptoms such as mood swings and increased irritability. Furthermore, one patient developed hemichorea which can be a rare presentation of cerebral hemiatrophy. Conclusions Cerebral hemiatrophy syndromes are a heterogeneous group of disorders that may also present with neuropsychiatric symptoms or hemichorea.