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Successful Treatment of Blepharospasm by Pallidal Neurostimulation
Author(s) -
Santos Ana Filipa,
Veiga Andreia,
Augusto Luís,
Vaz Rui,
Rosas Maria José,
Volkmann Jens
Publication year - 2016
Publication title -
movement disorders clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 18
ISSN - 2330-1619
DOI - 10.1002/mdc3.12297
Subject(s) - blepharospasm , neurostimulation , deep brain stimulation , neuroscience , medicine , dystonia , pallidotomy , psychology , physical medicine and rehabilitation , parkinson's disease , stimulation , disease
Blepharospasm, a focal dystonia characterized by involuntary orbicularis oculi muscle spasms, may vary in severity from a slightly bothersome condition to a disabling disorder that renders patients functionally blind. Botulinum toxin (BTX) injection, the gold-standard treatment, has a beneficial effect in 95% of patients. Oral medication is of limited efficacy. For individuals that do not respond, eyelid myectomy or upper-lid orbicularis muscle strip with subsequent eyebrow suspension are possible therapeutic options, although not always with acceptable results. Herein, we present the first case report of globus pallidus interna (GPi)-DBS surgery for isolated blepharospasm.