Successful Treatment of Blepharospasm by Pallidal Neurostimulation | Zendy

Santos Ana Filipa | Zendy; Veiga Andreia | Zendy; Augusto Luís | Zendy; Vaz Rui | Zendy; Rosas Maria José | Zendy; Volkmann Jens | Zendy

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Successful Treatment of Blepharospasm by Pallidal Neurostimulation

Author(s) -

Santos Ana Filipa,

Veiga Andreia,

Augusto Luís,

Vaz Rui,

Rosas Maria José,

Volkmann Jens

Publication year - 2016

Publication title -

movement disorders clinical practice

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.754

H-Index - 18

ISSN - 2330-1619

DOI - 10.1002/mdc3.12297

Subject(s) - blepharospasm , neurostimulation , deep brain stimulation , neuroscience , medicine , dystonia , pallidotomy , psychology , physical medicine and rehabilitation , parkinson's disease , stimulation , disease

Blepharospasm, a focal dystonia characterized by involuntary orbicularis oculi muscle spasms, may vary in severity from a slightly bothersome condition to a disabling disorder that renders patients functionally blind. Botulinum toxin (BTX) injection, the gold-standard treatment, has a beneficial effect in 95% of patients. Oral medication is of limited efficacy. For individuals that do not respond, eyelid myectomy or upper-lid orbicularis muscle strip with subsequent eyebrow suspension are possible therapeutic options, although not always with acceptable results. Herein, we present the first case report of globus pallidus interna (GPi)-DBS surgery for isolated blepharospasm.

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