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Pain in Parkinson's Disease: Current Concepts and a New Diagnostic Algorithm
Author(s) -
Mylius Veit,
Ciampi de Andrade Daniel,
Cury Rubens Gisbert,
Teepker Michael,
Ehrt Uwe,
Eggert Karla Maria,
Beer Serafin,
Kesselring Jürg,
Stamelou Maria,
Oertel Wolfgang H.,
Möller Jens Carsten,
Lefaucheur JeanPascal
Publication year - 2015
Publication title -
movement disorders clinical practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 18
ISSN - 2330-1619
DOI - 10.1002/mdc3.12217
Subject(s) - parkinson's disease , disease , medicine , physical therapy , quality of life (healthcare) , physical medicine and rehabilitation , neuropathic pain , psychology , nursing , pharmacology
Background Pain is a significant burden for patients with Parkinson's disease (PD) with a high impact on quality of life. The present article aims at summarizing epidemiological, pathophysiological, clinical, and neurophysiological data regarding pain in PD. Methods In this domain, a procedure of systematic assessment is still lacking for the syndromic diagnosis and should take into account pain characteristics, effects of dopaminergic treatment, motor fluctuations, and non‐PD‐associated pain. Findings We propose an original questionnaire addressing an algorithm suitable for daily clinical practice. The questionnaire is based on a three‐step approach addressing first the relationship between pain and PD (including temporal relationship with the course of the disease, association with motor fluctuations, and impact of antiparkinsonian treatment), before classifying pain into one of three main syndromes (i.e., musculoskeletal pain, psychomotor restlessness pain, and neuropathic pain). Conclusions The proposed questionnaire allows the characteristics of each pain type to be determined according to its relationship with the disease and its treatment. The validation of the clinical use of this questionnaire will be the goal of a forthcoming work.