Safe Administration of Botulinum Toxin Type A Injections During Pregnancy: A Report of Two Cases | Zendy

Krug Henriette | Zendy; Krause Patricia | Zendy; Kupsch Andreas | Zendy; Kühn Andrea A. | Zendy

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Safe Administration of Botulinum Toxin Type A Injections During Pregnancy: A Report of Two Cases

Author(s) -

Krug Henriette,

Krause Patricia,

Kupsch Andreas,

Kühn Andrea A.

Publication year - 2015

Publication title -

movement disorders clinical practice

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.754

H-Index - 18

ISSN - 2330-1619

DOI - 10.1002/mdc3.12135

Subject(s) - medicine , cervical dystonia , pregnancy , dystonia , botulinum toxin , anesthesia , first trimester , surgery , focal dystonia , obstetrics , fetus , genetics , biology , psychiatry

Local injections of botulinum toxin type A (Bo NT /A) are safe and efficacious to treat focal and segmental dystonia. However, there are no adequate studies in humans regarding the safety of Bo NT /A during pregnancy. Despite the fact that 25 case reports have been published on patients who received Bo NT /A injections during a total of 31 pregnancies, in only 3 patients were the injections continued beyond the first trimester. We report on 2 females with cervical and segmental dystonia who received Bo NT /A injections during pregnancy beyond the first trimester and gave birth to 2 healthy children.

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