Open AccessPutting an end to the Pseudomonas aeruginosa IQS controversy
Author(s) -
Cornelis Pierre
Publication year - 2020
Publication title -
microbiologyopen
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.881
H-Index - 36
ISSN - 2045-8827
DOI - 10.1002/mbo3.962
Subject(s) - siderophore , thiazole , pseudomonas aeruginosa , product (mathematics) , chemistry , biology , stereochemistry , bacteria , gene , biochemistry , genetics , mathematics , geometry
Despite published evidence that IQS (2‐(2‐hydroxylphenyl)‐thiazole‐4‐carbaldehyde) is in fact aeruginaldehyde, a by‐product of the siderophore pyochelin biosynthesis or degradation and that the ambABCDE genes are not responsible for IQS synthesis, several authors, including in top review journals, perpetuate the wrong information. I hope that this short comment will clarify the situation once and for all.