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Study of biocompatibility effect of nanocarbon particles on various cell types in vitro
Author(s) -
Tolkachov M.,
Sokolova V.,
Loza K.,
Korolovych V.,
Prylutskyy Y.,
Epple M.,
Ritter U.,
Scharff P.
Publication year - 2016
Publication title -
materialwissenschaft und werkstofftechnik
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.285
H-Index - 38
eISSN - 1521-4052
pISSN - 0933-5137
DOI - 10.1002/mawe.201600486
Subject(s) - biocompatibility , hela , carbon nanotube , fullerene , viability assay , nanoparticle , nanotechnology , scanning electron microscope , materials science , mesenchymal stem cell , cancer cell , mtt assay , chemistry , in vitro , biophysics , chemical engineering , cancer , microbiology and biotechnology , composite material , biochemistry , organic chemistry , biology , genetics , engineering
The viability of primary cells (human mesenchymal stem cells, hMSC, as a model for healthy cells) and a cancer cell line (human transformed cervix epithelial cells, HeLa, as a model for cancer cells) was studied with the MTT assay after the incubation with water‐soluble C 60 fullerenes and multi‐walled carbon nanotubes filled by iron, respectively. The size of the particles was determined by dynamic light scattering. The morphology of the cells incubated with nanocarbon particles was studied by scanning electron microscopy. The effect of C 60 fullerenes and Fe‐multi‐walled carbon nanotubes on the cells is depending on the concentration of applied nanoparticles.