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Ein poröses Kompositmaterial, bestehend aus Poly(D,L‐Lactid), Calciumcarbonat und Gentamycin als Knochenersatzmaterial
Author(s) -
Backhaus S.,
Annen T.,
Epple M.
Publication year - 2013
Publication title -
materialwissenschaft und werkstofftechnik
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.285
H-Index - 38
eISSN - 1521-4052
pISSN - 0933-5137
DOI - 10.1002/mawe.201300081
Subject(s) - porosity , composite number , materials science , calcium carbonate , leaching (pedology) , gentamicin , calcium , composite material , chemical engineering , chemistry , metallurgy , antibiotics , environmental science , soil science , engineering , soil water , biochemistry
Macroporous objects of poly(D,L‐lactide), PDLLA, and calcium carbonate were prepared by hot‐pressing (0% porosity), gas‐foaming (50% porosity), and a combination of gas‐foaming and salt leaching (70% porosity). They were loaded with 15 wt% of gentamicin without loss of the mechanical properties. The release of gentamicin occurred over several weeks, making this material suitable as a mechanically stable porous and degradable bone substitution material with antibacterial properties.