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Compartmentalized, multiphasic nanocolloids with potential applications in drug delivery and biomedical imaging
Author(s) -
Roh K.H.,
Yoshida M.,
Lahann J.
Publication year - 2007
Publication title -
materialwissenschaft und werkstofftechnik
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.285
H-Index - 38
eISSN - 1521-4052
pISSN - 0933-5137
DOI - 10.1002/mawe.200700245
Subject(s) - nanotechnology , drug delivery , electrohydrodynamics , nanoparticle , materials science , nanomedicine , biomedical engineering , chemistry , engineering , electrode
Nanoparticles are excellent candidates for drug delivery or biomedical imaging, because they often exhibit superb tuneability of critical properties, such as size, surface characteristics, degradation rate, and therefore drug release rates. We have recently developed a route towards fabrication of sub‐micron particles that relies on electrohydrodynamic co‐jetting. In this process, fluid manipulation in an electrical field is used to fabricate large quantities of multi‐compartment particles, where individual compartments can be independently loaded with different drugs or selectively surface‐modified. In this contribution, aspects of multifunctional particles for biomedical applications are reviewed and a specific focus is given to recent progress with compartmentalized, multiphasic nanocolloids in our laboratory.