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Kinetics and Mechanism of Oxidation of Glutahione by Waugh‐Type Enneamolybdomanganate(IV) in Aqueous Perchloric Acid
Author(s) -
More Shekhar S.,
Gurume Vashistha M.,
Gokavi Gavisiddappa S.
Publication year - 2020
Publication title -
macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 1022-1360
DOI - 10.1002/masy.202000008
Subject(s) - perchloric acid , chemistry , aqueous solution , protonation , reaction mechanism , kinetics , decomposition , inorganic chemistry , reaction intermediate , glutathione , reactive intermediate , order of reaction , ion , photochemistry , organic chemistry , catalysis , reaction rate constant , physics , quantum mechanics , enzyme
The reaction between enneamolybdomanganate(IV) and glutathione is studied under second‐order conditions in aqueous perchloric acid. The reaction first‐order in both the reactants and initiated through formation of a precursor complex. Protonated forms of both the reactants are found to be active as evidenced by the accelerating effect of increasing hydrogen ion concentration effect. The second step of the reaction is the slow decomposition of the complex leading to the formation of hydroxyl intermediate. The final product glutathione disulfide is formed in the fast third step as a result of reaction of intermediate with another glutathione cation.