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Povidone‐Phosphotungstic Acid Hybrid: An Efficient and Environmentally Benign Catalyst for the Synthesis of Quinazolinone Derivatives
Author(s) -
Kagne Raju,
Kalalawe Virbhadra,
Niwadange Sandeep,
Mahurkar Shreyash,
Munde Dashrath
Publication year - 2020
Publication title -
macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 1022-1360
DOI - 10.1002/masy.201900212
Subject(s) - quinazolinone , catalysis , phosphotungstic acid , aniline , methanol , chemistry , organic chemistry , condensation , fourier transform infrared spectroscopy , condensation reaction , solid acid , atom economy , nuclear chemistry , chemical engineering , physics , engineering , thermodynamics
In this research, a novel strategy for synthesis of quinazolinones has been formulated via one pot condensation of aromatic aldehydes, isatoic anhydride, and aniline by employing prepared povidone‐phosphotungstic acid (PVP‐PWA) hybrid as a novel solid acid heterogenous catalyst in methanol at 80 °C. The synthesized PVP‐PWA is confirmed by FTIR, XRD and studied for TGA, BET plots. The reaction is optimized for different solvents and loading of catalyst. The yields of all quinazolinone derivatives are observed in the range of 78–86%. All the synthesized quinazolinones are investigated by spectral data. The use of ecologically benign catalyst, good atom economy, environmental affordability, and easy work up makes this protocol sustainable.