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Thermal Characterization of Polymeric Coatings for Pharmaceutical Dosage Forms
Author(s) -
Fuliaş Adriana,
Vlase Gabriela,
Todea Anamaria,
Vlase Titus,
Ledeţi Ionuţ
Publication year - 2015
Publication title -
macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 1022-1360
DOI - 10.1002/masy.201400154
Subject(s) - thermal stability , materials science , fourier transform infrared spectroscopy , isothermal process , characterization (materials science) , dosage form , thermal analysis , chemical engineering , pharmaceutical formulation , chemical stability , thermal , chemistry , chromatography , nanotechnology , thermodynamics , physics , engineering
Summary Six pharmaceutical coatings, currently used in commercial pharmaceutical formulation were evaluated for thermal stability using TG/DTG/HF hyphenated techniques. The polymeric coatings were also evaluated by the means of UATR‐FTIR spectroscopy. TG/DTG/HF measurements were performed under non‐isothermal conditions from 40 up to 400 °C linearly at a heating rate of 10 °C · min −1 . The thermal stability of all studied samples that are currently used as coatings on the Romanian pharmaceutical industry was correlated with their chemical composition.