Premium
Chemistry Modification of PMMA‐g‐PEG copolymer
Author(s) -
Rosa Juliana dos Santos,
Silveira Benila Maria,
Novack Kátia Monteiro,
dos Santos Viviane Martins Rebello,
de Moraes Teixeira Leonardo César
Publication year - 2014
Publication title -
macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 1022-1360
DOI - 10.1002/masy.201300197
Subject(s) - copolymer , acetic anhydride , chemistry , polymer chemistry , acetic acid , polymer , reagent , methyl iodide , fourier transform infrared spectroscopy , iodide , chemical modification , organic chemistry , catalysis , chemical engineering , engineering
Summary Copolymers are polymers consisting of different repeat units and their production is usually motivated by the changing of polymers properties. An important application are the transportation of drugs within the organism with the aim of controlling the release of the substance. The synthesis of these new copolymers is based on simple semi‐synthesis and low cost. The synthetic routes are based on the interaction of the graft copolymer (PMMA‐g‐PEG) with a variety of reagents such as acetic anhydride, acetic acid, methyl iodide, sulfuric acid and hydrochloric acid. The products from these reactions of esterification, methylation, acetylation and halogenation will be characterized by Fourier‐transforminfrared spectroscopy (FTIR). The use of this technique allowed us to detect the main absorption bands related to the CO bonds, C‐Cl, R‐COOR and CO, thus confirming the efficiency of modification reactions of the graft copolymer chain.