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Synthesis and Study of New Copolymers Capable of Forming Molecular Complexes with DNA
Author(s) -
Davydova N.K.,
Sinitsyna O.V.,
Yaminsky I.V.,
Kalinina E.V.,
Zinoviev K.E.
Publication year - 2012
Publication title -
macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 1022-1360
DOI - 10.1002/masy.201251114
Subject(s) - copolymer , acrylamide , aqueous solution , polymer chemistry , dna , materials science , atomic force microscopy , polymer , chemistry , nanotechnology , organic chemistry , biochemistry , composite material
Summary: The possibility of creating the copolymers capable of specific interactions with DNA was studied. The copolymers of acrylamide and synthesized N‐substituted acrylamides were obtained by free‐radical copolymerization in aqueous medium. Using atomic force microscopy it was demonstrated that some of the obtained copolymers form molecular complexes with the bacteriophage lambda DNA. Potentially, the copolymers can be used for detection of DNA in sensing applications.