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Preparation of Three‐Dimensional Scaffolds from Degradable Poly(ether)esterurethane by Thermally‐Induced Phase Separation
Author(s) -
Luetzow Karola,
Weigel Thomas,
Schossig Michael,
Kratz Karl,
Lendlein Andreas
Publication year - 2011
Publication title -
macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 1022-1360
DOI - 10.1002/masy.201100051
Subject(s) - polymer , materials science , ether , porosity , sublimation (psychology) , chemical engineering , solvent , polymer chemistry , molar mass distribution , phase (matter) , composite material , chemistry , organic chemistry , psychology , engineering , psychotherapist
Highly porous scaffolds with an overall volume up to 30 cm 3 and porosities in the range from 80% to 93% were prepared from degradable poly(ether)esterurethane by thermally‐induced phase separation (TIPS) and subsequent solvent sublimation. The variation of the polymer concentration when applying a fixed TIPS cooling protocol led to an adjustment in pore size as well as in pore size distribution. While polymer concentrations of 5, 7.5 and 10 wt% resulted in averaged pore sizes ranging from 70 to 90 µm with a broad pore size distribution (according to µ‐CT analysis) for polymer concentrations of 15 wt% a significant lower averaged pore size of 50 µm with a narrow pore size distribution was obtained.