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Thermoresponsive Hydrogels from Physical Mixtures of Self‐Assembling Peptide and its Conjugate with PNIPAAm
Author(s) -
Maslovskis A.,
Saiani A.,
Miller A.F.
Publication year - 2010
Publication title -
macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 1022-1360
DOI - 10.1002/masy.201051035
Subject(s) - conjugate , self healing hydrogels , rheology , materials science , peptide , polymer , phase (matter) , poly(n isopropylacrylamide) , chemical engineering , polymer chemistry , copolymer , chemistry , composite material , organic chemistry , mathematical analysis , biochemistry , mathematics , engineering
Abstract The phase behavior and rheology of a range of physical mixtures of self‐assembling octapeptide FEFEFKFK and its conjugate with the thermoresponsive polymer poly( N ‐isopropylacrylamide) (PNIPAAM) have been studied. These systems typically combined the thermo‐responsive character of PNIPAAM and the gelling property of octapeptides where both the elastic behavior and macroscopic melting of the system could be controlled by varying the ratio of pure peptide to peptide‐polymer conjugate.