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Nanostructured Materials for Skeletal Repair
Author(s) -
Brandt Joerg,
Michler Goerg,
Vogel Juergen,
Henning Sven
Publication year - 2010
Publication title -
macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 1022-1360
DOI - 10.1002/masy.201050810
Subject(s) - microscale chemistry , cartilage , extracellular matrix , regenerative medicine , regeneration (biology) , materials science , bone matrix , tissue repair , tissue engineering , nanotechnology , biomedical engineering , microbiology and biotechnology , anatomy , medicine , stem cell , biology , mathematics education , mathematics
The treatment of bone and cartilage defects with bioengineered constructs of artificial scaffolds and autogenous cells became the main challenge of contemporary regenerative medicine. Early defect repair may prevent secondary injury. Recent studies could prove that bone and cartilage cells are sensitive to microscale and nanoscale patterns of surface topography and chemical structure. Nanostructured materials provide an environment for tissue regeneration mimicking the physiological range of extracellular matrix. The article reviews several studies substantiating the superiority of nanostructured materials for bone and cartilage repair along with own results on cell attachment.