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New Biocompatible Microgels
Author(s) -
Imaz Ainara,
Forcada Jacqueline
Publication year - 2009
Publication title -
macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 1022-1360
DOI - 10.1002/masy.200950711
Subject(s) - biocompatible material , ethylene glycol , monomer , drug delivery , materials science , polymerization , polymer chemistry , chemical engineering , hydrolysis , characterization (materials science) , nanotechnology , chemistry , polymer , organic chemistry , biomedical engineering , composite material , medicine , engineering
Abstract Summary: Microgel particles have received an increasing interest in the biomedical field. Temperature‐sensitive microgels gained particular interest due to their potential use as controlled drug delivery systems. With the objective to produce new thermoresponsive biocompatible microgels, the synthesis and characterization of two families of microgel particles obtained by using N ‐vinylcaprolactam (VCL) as main monomer and N,N ′‐methylenbisacrylamide (BA) or poly(ethylene glycol) diacrylate (PEGDA) as crosslinkers are described. Evidence of hydrolysis VCL during polymerization is also presented.