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Surface Modification of Polydimethylsiloxane Substrates with Nonfouling Poly(Poly(ethylene glycol)methacrylate) Brushes
Author(s) -
Tugulu Stefano,
Klok HarmAnton
Publication year - 2009
Publication title -
macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 1022-1360
DOI - 10.1002/masy.200950516
Subject(s) - polydimethylsiloxane , ethylene glycol , methacrylate , materials science , atom transfer radical polymerization , polymer chemistry , polymer , polymerization , layer (electronics) , chemical engineering , coating , substrate (aquarium) , protein adsorption , composite material , oceanography , engineering , geology
This contribution presents a new strategy to grow nonfouling poly (poly(ethylene glycol)methacrylate) (PPEGMA) brushes from polydimethylsiloxane (PDMS) substrates. The strategy presented here is based on the use of a sequence of vapor deposition/hydrolysis cycles to generate a surface‐confined atom transfer radical polymerization (ATRP)‐initiator functionalized interpenetrating polymer network (IPN) layer. In contrast to most other approaches that have been developed to graft thin polymer layers from PDMS substrates, this technique obviates the need for UV/ozone pretreatment of the PDMS substrate. It is shown that the surface‐confined ATRP‐initiator functionalized IPN layer can be used to grow PPEGMA brushes in a controlled fashion and that the resulting PPEGMA coating significantly reduces nonspecific protein adsorption as compared to unmodified PDMS substrates.