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Properties of a Water‐Soluble Paclitaxel Conjugate in Aqueous Solution and its Interaction with Serum Albumin
Author(s) -
Hess M.,
Jo B.W.,
Wermeckes B.,
Dehne S.,
Sohn J.S.,
Wunderlich S.,
Zähres M.
Publication year - 2005
Publication title -
macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 1022-1360
DOI - 10.1002/masy.200590023
Subject(s) - conjugate , aqueous solution , paclitaxel , chemistry , albumin , serum albumin , solid state , polymer , drug , chromatography , cancer , pharmacology , organic chemistry , biochemistry , medicine , mathematics , mathematical analysis
A summary of the most recent investigations of conformation and solution properties of a polymer conjugate of the anti‐cancer drug paclitaxel is given. First results of spectroscopic studies of interaction with model proteins in the solid state and in solution are discussed.