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A qualitative study to the influence of molar mass on retention in gradient polymer elution chromatography (GPEC)
Author(s) -
Klumperman Bert,
Cools Paul,
Philipsen Harry,
Staal Wim
Publication year - 1996
Publication title -
macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 1022-1360
DOI - 10.1002/masy.19961100102
Subject(s) - molar mass , elution , chromatography , gradient elution , polymer , chemistry , materials science , high performance liquid chromatography , organic chemistry
Gradient Polymer Elution Chromatography (GPEC) appears to be a powerful method for the determination of chemical composition distributions (CCD) of high molar mass copolymers. In order to perform these experiments, molar mass dependence of the retention time must be minimized. It is shown that variation in solvent and non‐solvent strength is a powerful method for adjusting the molar mass dependence. There appears to be a relation between molar mass dependence of retention behavior in GPEC on one hand and solubility under critical solvent conditions on the other hand. This phenomenon can be explained qualitatively from the important precipitation/redissolution mechanism in GPEC.