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Spectroscopic and thermodynamic characterization of the adsorption of plasma proteins onto cellulosic substrates
Author(s) -
Müller M.,
Werner C.,
Grundke K.,
Eichhorn K. J.,
Jacobasch H.J.
Publication year - 1996
Publication title -
macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 1022-1360
DOI - 10.1002/masy.19961030108
Subject(s) - sorption , cellulose , adsorption , zeta potential , chemistry , fourier transform infrared spectroscopy , contact angle , human serum albumin , chemical engineering , cellulosic ethanol , kinetics , materials science , chromatography , organic chemistry , physics , quantum mechanics , nanoparticle , engineering
The sorption of the plasma proteins human serum albumin (HSA) and human fibrinogen (FIB) onto hemodialytic cellulosic substrates was investigated by the surface sensitive ATR‐FTIR‐spectroscopy. By means of this method we monitored the protein sorption kinetics onto acetylated and unmodified cellulose (AKZO‐NOBEL). Furthermore, secondary structure alterations of the adsorbed proteins as well as changes of the composition in sorbed layers consisting of two proteins were detected. These findings were compared with results of the zeta potential and contact angle measurements on comparable sorption experiments.