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Biosynthesis of new polymers of controlled molecular structure
Author(s) -
Dougherty Michael J.,
Kothakota Srinivas,
Krejchi Mark T.,
Zhang Guanghui,
Mason Thomas L.,
Tirrell David A.,
Fournier Maurille J.
Publication year - 1992
Publication title -
makromolekulare chemie. macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 0258-0322
DOI - 10.1002/masy.19920620121
Subject(s) - biosynthesis , polymer , chemistry , computational biology , biochemistry , stereochemistry , gene , biology , organic chemistry
Abstract This paper describes the use of artificial genes to direct bacterial synthesis of new polypeptides of precisely defined molecular structure. This approach has been applied to three problems in polymer chemistry and physics: i) control of chain folding in crystalline polymers, ii) biosynthesis of polypeptides containing unnatural amino acids, and iii) preparation of monodisperse helical polymers.