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Synthesis and evaluation of polyamine graft and block copolymers as novel biomaterials for cell separation
Author(s) -
Tsuruta Teiji
Publication year - 1990
Publication title -
makromolekulare chemie. macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 0258-0322
DOI - 10.1002/masy.19900330121
Subject(s) - copolymer , polyamine , methacrylate , adhesion , field flow fractionation , polymer chemistry , fractionation , chemistry , materials science , chemical engineering , chromatography , organic chemistry , polymer , biochemistry , engineering
Graft copolymer (HA) composed of 2‐hydroxyethyl methacrylate (HEMA) and a polyamine exhibits unique biospecific behavior at the interface with living cells. In the present paper, the writer will discuss on four topics : (i) effective separation of rat lymphocyte subpopulations by using HA copolymer; (ii) surface analysis of HA copolymers by ESCA and streaming potential measurements; (iii) a hybrid field flow fractionation/adhesion chromatography technique; and (iv) specific cellular recognition of poly(HEMA)‐graft‐quaternized polyamine copolymer (HQA)