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Modification of polyetherurethane for endothelial cell seeding
Author(s) -
Klee D.,
Breuers W.,
Höcker H.,
Mittermayer C.
Publication year - 1988
Publication title -
makromolekulare chemie. macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 0258-0322
DOI - 10.1002/masy.19880190114
Subject(s) - polymer , monolayer , surface modification , materials science , adhesion , chemical engineering , microporous material , scanning electron microscope , polymer chemistry , covalent bond , polymerization , chemistry , nanotechnology , composite material , organic chemistry , engineering
Until now no synthetic polymer surface was available suitable for cardiovascular implantation which effectively prevents microthrombosis for a long time. The presented concept of our work is to develop a polymer surface to promote the growth of a durable endothelial cell monolayer which would be formed on the prothesis prior to implantation. A microporous polyetherurethane foil is being used as carrier polymer for the cell monolayer. Suitable functional groups are grafted on the polymer surface by plasma polymerization. The success of the first modification steps is followed by ESCA‐analysis and scanning electron microscopy. The modified carrier polymer is the starting material for covalent binding of biopolymers which react as adhesion supporter between the synthetic polymer surface and the endothelial cells.