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Recent advances in the study of biopolymers
Author(s) -
KatchalskiKatzir Ephraim
Publication year - 1988
Publication title -
makromolekulare chemie. macromolecular symposia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.257
H-Index - 76
eISSN - 1521-3900
pISSN - 0258-0322
DOI - 10.1002/masy.19880190103
Subject(s) - nucleic acid , macromolecule , flexibility (engineering) , dna , chemistry , computational biology , nanotechnology , biology , biochemistry , materials science , mathematics , statistics
In describing some of the macromolecular characteristics of the nucleic acids, particularly DNA, and of representative proteins, the following aspects are discussed: computer‐assisted modeling as a useful tool for depicting the three‐dimensional structures and macromolecular characteristics of biopolymers; conformational flexibility in biopolymers; parameters determining protein recognition; and the importance of the three‐dimensional structure of antibodies, enzymes, receptors, ion channels, and proteins interacting with nucleic acids, in determining their characteristic biological functions. Many of the problems raised by molecular biologists concerning the mode of action of biopolymers could be tackled by polymer chemists, because of their experience in dealing theoretically as well as experimentally with synthetic and native high molecular weight compounds.