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Plasma‐based ambient ionization mass spectrometry in bioanalytical sciences
Author(s) -
Smoluch Marek,
Mielczarek Przemyslaw,
Silberring Jerzy
Publication year - 2015
Publication title -
mass spectrometry reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.035
H-Index - 126
eISSN - 1098-2787
pISSN - 0277-7037
DOI - 10.1002/mas.21460
Subject(s) - chemistry , bioanalysis , mass spectrometry , environmental chemistry , chromatography , analytical chemistry (journal) , ambient ionization , ionization , chemical ionization , organic chemistry , ion
Plasma‐based ambient ionization mass spectrometry techniques are gaining growing interest due to their specific features, such as the need for little or no sample preparation, its high analysis speed, and the ambient experimental conditions. Samples can be analyzed in gas, liquid, or solid forms. These techniques allow for a wide range of applications, like warfare agent detection, chemical reaction control, mass spectrometry imaging, polymer identification, and food safety monitoring, as well as applications in biomedical science, e.g., drug and pharmaceutical analysis, medical diagnostics, biochemical analysis, etc. Until now, the main drawback of plasma‐based techniques is their quantitative aspect, but a lot of efforts have been done to improve this obstacle. © 2015 Wiley Periodicals, Inc. Mass Spec Rev 35: 22–34, 2016.