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Plasma‐based ambient mass spectrometry techniques: The current status and future prospective
Author(s) -
Ding Xuelu,
Duan Yixiang
Publication year - 2013
Publication title -
mass spectrometry reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.035
H-Index - 126
eISSN - 1098-2787
pISSN - 0277-7037
DOI - 10.1002/mas.21415
Subject(s) - chemistry , mass spectrometry , reagent , plasma , environmental chemistry , analytical chemistry (journal) , dielectric barrier discharge , glow discharge , chromatography , nanotechnology , organic chemistry , physics , materials science , electrode , quantum mechanics
Plasma‐based ambient mass spectrometry is emerging as a frontier technology for direct analysis of sample that employs low‐energy plasma as the ionization reagent. The versatile sources of ambient mass spectrometry (MS) can be classified according to the plasma formation approaches; namely, corona discharge, glow discharge, dielectric barrier discharge, and microwave‐induced discharge. These techniques allow pretreatment‐free detection of samples, ranging from biological materials (e.g., flies, bacteria, plants, tissues, peptides, metabolites, and lipids) to pharmaceuticals, food‐stuffs, polymers, chemical warfare reagents, and daily‐use chemicals. In most cases, plasma‐based ambient MS performs well as a qualitative tool and as an analyzer for semi‐quantitation. Herein, we provide an overview of the key concepts, mechanisms, and applications of plasma‐based ambient MS techniques, and discuss the challenges and outlook. © 2013 Wiley Periodicals, Inc. Mass Spec Rev 34: 449–473, 2015.