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Atmospheric pressure ion sources
Author(s) -
Covey Thomas R.,
Thomson Bruce A.,
Schneider Bradley B.
Publication year - 2009
Publication title -
mass spectrometry reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.035
H-Index - 126
eISSN - 1098-2787
pISSN - 0277-7037
DOI - 10.1002/mas.20246
Subject(s) - chemistry , atmospheric pressure , ionization , atmospheric pressure chemical ionization , chemical ionization , limiting , mass spectrometry , atmospheric chemistry , ion , instrumentation (computer programming) , ambient ionization , analytical chemistry (journal) , environmental chemistry , meteorology , organic chemistry , mechanical engineering , chromatography , physics , computer science , ozone , engineering , operating system
This review of atmospheric pressure ion sources discusses major developments that have occurred since 1991. Advances in the instrumentation and understanding of the key physical principles are the primary focus. Developments with electrospray and atmospheric pressure chemical ionization and variations encompassing adaptations for surface analysis, ambient air analysis, high throughput, and modification of the ionization mechanism are covered. An important and limiting consequence of atmospheric pressure chemical ionization, chemical noise, is discussed as is techniques being employed to ameliorate the problem. Ion transfer and transport from atmospheric pressure into deep vacuum is an area undergoing constant improvement and refinement so is given considerable consideration in this review. © 2009 Wiley Periodicals, Inc., Mass Spec Rev 28:870–897, 2009