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Computational view of surface based organic mass spectrometry
Author(s) -
Garrison Barbara J.,
Postawa Zbigniew
Publication year - 2008
Publication title -
mass spectrometry reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.035
H-Index - 126
eISSN - 1098-2787
pISSN - 0277-7037
DOI - 10.1002/mas.20165
Subject(s) - chemistry , mass spectrometry , cluster (spacecraft) , secondary ion mass spectrometry , surface science , analytical chemistry (journal) , static secondary ion mass spectrometry , molecule , chemical physics , environmental chemistry , surface (topology) , chromatography , organic chemistry , geometry , mathematics , computer science , programming language
Surface based mass spectrometric approaches fill an important niche in the mass analysis portfolio of tools. The particular niche depends on both the underlying physics and chemistry of molecule ejection as well as experimental characteristics. In this article, we use molecular dynamics computer simulations to elucidate the fundamental processes giving rise to ejection of organic molecules in atomic and cluster secondary ion mass spectrometry (SIMS), massive cluster impact (MCI) mass spectrometry, and matrix‐assisted laser desorption ionization (MALDI) mass spectrometry. This review is aimed at graduate students and experimental researchers. © 2008 Wiley Periodicals, Inc., Mass Spec Rev 27: 289–315, 2008