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Intramolecular Folding of Coil‐Helix Block Copolymers Induced by Quadrupole Interactions
Author(s) -
Wang Chengyuan,
Weck Marcus
Publication year - 2021
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.202100368
Subject(s) - copolymer , atom transfer radical polymerization , folding (dsp implementation) , intramolecular force , polymerization , polymer chemistry , materials science , helix (gastropod) , small angle x ray scattering , isocyanide , dynamic light scattering , nuclear magnetic resonance spectroscopy , polymer , scattering , chemistry , nanotechnology , stereochemistry , physics , composite material , ecology , optics , snail , electrical engineering , biology , engineering , nanoparticle
True tertiary architectures with defined local secondary structures are rare in synthetic systems. Adapting well‐developed synthetic building blocks and controlling their folding through diverse interactions can be a general approach toward this goal. In this contribution, the synthesis of 3D hierarchical assemblies with distinct secondary domains formed through the intramolecular folding of a block copolymer containing a coil‐like poly(styrene) (PS) block with a helical poly(isocyanide) block induced by phenyl‐pentafluorophenyl quadrupole interactions is reported. The PS block is prepared via atom‐transfer radical polymerization and end functionalized with a nickel complex that serves as a macroinitiator for the polymerization of chiral isocyanides bearing pentafluorophenyl pendants. The folding behavior of the coil‐helix block copolymers is investigated by dynamic light scattering, NMR spectroscopy, wide‐angle X‐ray scattering, and differential scanning calorimetry.