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Thermoresponsive Cationic Block Copolymer Brushes for Temperature‐Modulated Stem Cell Separation
Author(s) -
Nagase Kenichi,
Ota Ayumu,
Hirotani Tadashi,
Yamada Sota,
Akimoto Aya Mizutani,
Kanazawa Hideko
Publication year - 2020
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.202070043
Subject(s) - copolymer , cationic polymerization , brush , polymer chemistry , materials science , lower critical solution temperature , polymer brush , chemical engineering , polymer , polymerization , composite material , engineering
Front Cover : In article number 2000308 by Kenichi Nagase and co‐workers, functional thermoresponsive‐cationic block copolymer brushes are fabricated by two steps of surface‐initiated ATRP of N,N ‐dimethylaminopropyl acrylamide and N ‐isopropylacrylamide. All three types of tested cells adhere to the copolymer brush at 37 °C and selective detachment of mesenchymal stem cells from the copolymer brush occurs at 20 °C. Thus, the copolymer brush can be useful as an effective tool to separate stem cells from contaminant cells.