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Enzyme Responsive Inverse Opal Hydrogels
Author(s) -
Pei Yi,
Molley Thomas G.,
Kilian Kristopher A.
Publication year - 2020
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201900555
Subject(s) - self healing hydrogels , ethylene glycol , materials science , nanotechnology , colloid , photonic crystal , colloidal crystal , structural coloration , polymer , inverse , chemical engineering , polymer chemistry , composite material , optoelectronics , geometry , mathematics , engineering
Structured color in nature is controlled by nano‐ and micro‐structured interfaces giving rise to a photonic bandgap. This study presents a biomimetic optical material based on polymeric inverse opals that respond to enzyme activity. Polymer colloids provide a template in which acryloyl‐functionalized poly(ethylene glycol) is integrated; dissolution of the colloids leads to a hydrogel inverse opal that can be lithographically patterned using transfer printing. Incorporating enzyme substrates within the voids provides a material that responds to the presence of proteases through a shift in the optical properties.