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Chemical Surface Modification of Polymeric Biomaterials for Biomedical Applications
Author(s) -
Sun Wei,
Liu Wenying,
Wu Zhaoqiang,
Chen Hong
Publication year - 2020
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201900430
Subject(s) - biomaterial , biocompatible material , biofouling , surface modification , grafting , materials science , nanotechnology , polymer science , chemical modification , polymer , polymer chemistry , chemical engineering , chemistry , biomedical engineering , composite material , engineering , biochemistry , membrane
This review focuses on the attachment of polymer brushes to polymeric biomaterial substrates by chemical surface modification methods for biomedical applications. In the first part of this paper, a general introduction to the synthesis of polymer brushes is given. Thereafter, a comprehensive overview of recent work on the chemical surface modification of polymeric biomaterials, with a focus on “grafting‐to,” “grafting‐from,” and “grafting‐through” strategies, is provided. Finally, some representative cutting‐edge biomedical applications of modified polymeric biomaterials, mainly including antifouling materials and biocompatible materials, are highlighted. On the basis of this literature study, a perspective on future trends in this field is provided.