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Effective Separation of Enantiomers Based on Novel Chiral Hierarchical Porous Metal‐Organic Gels
Author(s) -
Ma Yu,
Li Aijie,
Gao Xiaonan,
Huang Fang,
Kuang Xuan,
Yang Peng,
Yue Jieyu,
Tang Bo
Publication year - 2019
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201800862
Subject(s) - microporous material , enantiomer , metal organic framework , porosity , polymer , organic polymer , materials science , metal , chemical engineering , porous medium , chiral stationary phase , high performance liquid chromatography , phase (matter) , nanotechnology , chemistry , chromatography , organic chemistry , adsorption , engineering
Metal‐organic gel (MOG) matrices with tunable pore sizes ranging from micropore to macropore, derived from microporous metal‐organic coordination polymers (PCPs), has attracted great attention for their enhanced pore accessibility compared with the multifunctional PCP materials themselves. The enhanced pore accessibility of chiral MOGs is especially imperative for mass transfer applications, including enantioseparations and purifications. Here, for the first time, a novel hierarchical porous MOG‐coated SiO 2 , derived from a chiral metal‐organic coordination polymer, is employed as chiral stationary phase for effective high‐performance liquid chromatography (HPLC) separation of enantiomers. The selected enantiomers with diverse functional groups are all efficiently separated in a few minutes with significantly higher resolution.