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Studies on the Biocompatibility of Poly(diethyl vinyl‐phosphonate) with a New Fluorescent Marker
Author(s) -
Schwarzenböck Christina,
Vagin Sergei I.,
Heinz Werner R.,
Nelson Peter J.,
Rieger Bernhard
Publication year - 2018
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201800259
Subject(s) - biocompatibility , fluorescence , phosphonate , chromophore , surface modification , polymerization , polymer , materials science , conjugate , polymer chemistry , chemistry , photochemistry , organic chemistry , mathematical analysis , physics , mathematics , quantum mechanics
Utilization of group transfer polymerization for the synthesis of poly(diethyl vinylphosphonate) (PDEVP) allows its controlled end‐group functionalization. Thus, a new fluorescent chromophore/PDEVP conjugate is prepared and subjected to biocompatibility tests on two different human cell lines. In contrast to the previous studies, the tagged polymer is not absorbed by cells from the solution and has nearly no impact on cell mortality rate.