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Forecastable and Guidable Bubble‐Propelled Microplate Motors for Cell Transport
Author(s) -
Hu Narisu,
Zhang Bin,
Gai Meiyu,
Zheng Ce,
Frueh Johannes,
He Qiang
Publication year - 2017
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201600795
Subject(s) - hela , bubble , cell , biophysics , magnetic field , nanotechnology , chemistry , physics , materials science , biology , mechanics , biochemistry , quantum mechanics
Cell transport is important to renew body functions and organs with stem cells, or to attack cancer cells with immune cells. The main hindrances of this method are the lack of understanding of cell motion as well as proper transport systems. In this publication, bubble‐propelled polyelectrolyte microplates are used for controlled transport and guidance of HeLa cells. Cells survive attachment on the microplates and up to 22 min in 5% hydrogen peroxide solution. They can be guided by a magnetic field whereby increased friction of cells attached to microplates decreases the speed by 90% compared to pristine microplates. The motion direction of the cell–motor system is easier to predict due to the cell being opposite to the bubbles.