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Amino‐Acid‐Based Polymerizable Surfactants for the Synthesis of Chiral Nanoparticles
Author(s) -
Preiss Laura C.,
Wagner Manfred,
Mastai Yitzhak,
Landfester Katharina,
MuñozEspí Rafael
Publication year - 2016
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201600210
Subject(s) - enantioselective synthesis , crystallization , nucleation , pulmonary surfactant , nanoparticle , materials science , amino acid , chemical engineering , polymer chemistry , combinatorial chemistry , organic chemistry , chemistry , nanotechnology , catalysis , biochemistry , engineering
Amino‐acid‐based chiral surfactants with polymerizable moieties are synthesized, and a versatile approach to prepare particles thereof with a chiral surface functionality is presented. As an example of an application, the synthesized particles are tested for their ability as nucleating agents in the enantioselective crystallization of amino acid conglomerate systems, taking rac ‐asparagine as a model system. Particles resulting from chiral surfactants with different tail groups are compared and the results demonstrate that only the chiral nanoparticles made of the polymerizable surfactant are able to act efficiently as nucleation agent in enantioselective crystallization.