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Macromol. Rapid Commun. 17/2015
Author(s) -
Yang Liye,
Li Wenying,
Huang Yanyu,
Zhou Yangliang,
Chen Tianfeng
Publication year - 2015
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201570067
Subject(s) - polyethylenimine , covalent bond , conjugated system , linker , fluorescence , selectivity , combinatorial chemistry , aqueous solution , chemistry , peptide , biophysics , nanotechnology , stereochemistry , materials science , biochemistry , biology , organic chemistry , polymer , computer science , physics , transfection , quantum mechanics , catalysis , gene , operating system
Front Cover: A RGD peptide is covalently conjugated to a fluorescent selenocompound BSeC using polyethylenimine as a linker, which forms a nanosystem in aqueous solution. This rational design effectively enhances the selective cellular uptake of BSeC in human glioma cells, and increases its selectivity between cancer and normal cells. Further details can be found in the article by L. Yang, W. Li, Y. Huang, Y. Zhou, and T. Chen* on page 1559.