Premium
Supramolecular Nanoparticles via Single‐Chain Folding Driven by Ferrous Ions
Author(s) -
Wang Fei,
Pu Hongting,
Jin Ming,
Wan Decheng
Publication year - 2016
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201500616
Subject(s) - supramolecular chemistry , ferrous , folding (dsp implementation) , nanoparticle , chain (unit) , ion , materials science , single chain , nanotechnology , supramolecular assembly , polymer chemistry , chemistry , crystallography , organic chemistry , crystal structure , physics , engineering , antibody , astronomy , electrical engineering , immunology , biology
Single‐chain nanoparticles can be obtained via single‐chain folding assisted by intramolecular crosslinking reversibly or irreversibly. Single‐chain folding is also an efficient route to simulate biomacromolecules. In present study, poly( N ‐hydroxyethylacrylamide‐co‐4′‐(propoxy urethane ethyl acrylate)‐2,2′:6′,2″‐terpyridine) (P(HEAm‐co‐EMA‐Tpy)) is synthesized via reversible addition fragmentation chain transfer polymerization. Single‐chain folding and intramolecular crosslinking of P(HEAm‐co‐EMA‐Tpy) are achieved via metal coordination chemistry. The intramolecular interaction is characterized on ultraviolet/visible spectrophotometer (UV–vis spectroscopy), proton nuclear magnetic resonance ( 1 H NMR), and differential scanning calorimetry (DSC). The supramolecular crosslinking mediated by Fe 2+ plays an important role in the intramolecular collapsing of the single‐chain and the formation of the nanoparticles. The size and morphology of the nanoparticles can be controlled reversibly via metal coordination chemistry, which can be characterized by dynamic light scattering (DLS), transmission electron microscope (TEM), and atomic force microscope (AFM).