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Macromol. Rapid Commun. 2/2014
Author(s) -
Trinh Thanh Tam,
Oswald Laurence,
ChanSeng Delphine,
Lutz JeanFrançois
Publication year - 2014
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201470006
Subject(s) - monomer , amide , chemistry , sequence (biology) , polymer chemistry , combinatorial chemistry , materials science , computer science , organic chemistry , polymer , biochemistry
Front Cover: A possible strategy to encrypt information at the molecular level is the creation of a binary code using two co‐monomers defined as 0 and 1. As a proof of principle, sequence‐defined oligo(triazole amide)s are synthesized via a stepwise solid‐phase iterative process. In this approach, a reactive spacer, namely 1‐amino‐11‐azido‐3,6,9‐trioxaundecane, is reacted with either 4‐pentynoic acid (non‐coding monomer) or 2‐methyl‐4‐pentynoic acid (coding monomer). All possible information triads, 000, 001, 010, 100, 011, 101, 110, and 111 can be obtained using this approach. Further details can be found in the article by T. T. Trinh, L. Oswald, D. Chan‐Seng, and J.‐F. Lutz* on page 141.