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Preparation of Multilayered Polymeric Structures Using a Novel Four‐Needle Coaxial Electrohydrodynamic Device
Author(s) -
Labbaf Sheyda,
Ghanbar Hanif,
Stride Eleanor,
Edirisinghe Mohan
Publication year - 2014
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201300777
Subject(s) - polycaprolactone , materials science , electrohydrodynamics , coaxial , polymer , polyethylene glycol , nanotechnology , polylactic acid , polyethylene terephthalate , chemical engineering , scanning electron microscope , composite material , chemistry , computer science , telecommunications , electrode , engineering
Coaxial four‐needle electrohydrodynamic forming is applied for the first time to prepare layered structures in both particle and fiber form. Four different biocompatible polymers, polyethylene glycol, poly (lactic‐ co ‐glycolic acid), polycaprolactone, and polymethylsilsesquioxane, are used to generate four distinct layers confirmed using transmission and scanning electron microscopy combined with focused ion beam milling. The incorporation and release of different dyes within the polymeric system of four layers are demonstrated, something that is much desired in modern applications such as the polypill where multiple active pharmaceutical ingredients can be combined to treat numerous diseases.