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Simultaneous Polymerization‐Induced Self‐Assembly (PISA) and Guest Molecule Encapsulation
Author(s) -
Karagoz Bunyamin,
Boyer Cyrille,
Davis Thomas P.
Publication year - 2014
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201300730
Subject(s) - encapsulation (networking) , polymerization , self assembly , materials science , molecule , polymer chemistry , nanotechnology , chemical engineering , chemistry , polymer , organic chemistry , composite material , computer science , engineering , computer network
Nanoparticles with various morphologies such as micelles, worm‐like/rod‐like and spherical vesicles are made using a polymerization‐induced self‐assembly (PISA) approach via a one‐pot RAFT dispersion polymerization. On polymerization/self‐assembly, we report a concurrent highly efficient loading of guest molecules within the nanoparticle structures. Different nanoparticle morphologies, such as spherical micelles, worm‐like, rod‐like, and spherical vesicles, are achieved by gradually increasing the number‐average degree of polymerization (DP n ) of the PST block via increasing polymerization times (in a poor solvent) as determined by transmission electron microscopy (TEM) and dynamic light scattering (DLS) measurements. In parallel, a guest molecule (Nile Red) is encapsulated during the polymerization without disturbing the morphology or the polymerization kinetics.