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pH‐Responsive Self‐Assembly by Molecular Recognition on a Macroscopic Scale
Author(s) -
Zheng Yongtai,
Hashidzume Akihito,
Harada Akira
Publication year - 2013
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201300324
Subject(s) - protonation , cyclodextrin , polyacrylamide gel electrophoresis , polyacrylamide , chemistry , gel electrophoresis , fluorescence , polymer chemistry , chemical engineering , chromatography , biochemistry , organic chemistry , enzyme , physics , ion , quantum mechanics , engineering
Macroscopic pH‐responsive self‐assembly is successfully constructed by polyacrylamide(pAAm)‐based gels carrying dansyl (Dns) and β‐cyclodextrin (βCD) residues, which are represented as Dns‐gel and βCD‐gel, respectively. Dns‐gel and βCD‐gel assemble together at pH ≥ 4.0, but disassemble at pH ≤ 3.0. The adhesion strengths for pairs of Dns‐gel/βCD‐gel increase with increasing pH. The fluorescence study on the model system of pAAm modified with 1 mol% Dns moieties (pAAm/Dns) reveals that Dns residues are protonated at a lower pH, which results in the reduction in binding constant ( K ) for Dns residues and βCD.