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Reactive Graphene Oxide Nanosheets: A Versatile Platform for the Fabrication of Graphene Oxide–Biomolecule/Polymer Nanohybrids
Author(s) -
Xu Li Qun,
Zhang Bin,
Chen Yu,
Neoh KoonGee,
Kang EnTang,
Fu Guo Dong
Publication year - 2013
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201200635
Subject(s) - graphene , biomolecule , materials science , oxide , polymer , nanotechnology , fabrication , polymer chemistry , chemical engineering , composite material , medicine , alternative medicine , pathology , engineering , metallurgy
Graphene oxide (GO) nanosheets can be functionalized with reactive pentafluorophenyl ester via esterification of the carboxylic groups. The resulting reactive GO nanosheets provide a versatile platform for grafting of amino‐containing polymers or biomolecules via ester–amine coupling. Coupling of poly[(9,9‐dioctylfluorene)‐ alt ‐(4‐amino‐phenylcarbazole)] (PFCz‐NH 2 ), amino‐terminated hyperbranched polyglycerol (HPG‐NH 2 ), and lysozyme (Lyz) was illustrated. The Al/GO‐ g ‐PFCz/ITO sandwich thin‐film device exhibits bistable electrical switching and rewritable memory effects. The GO‐ g ‐Lyz nanohybrids exhibit high bactericidal efficacy against S. aureus and E. coli , while the GO‐ g ‐HPG nanohybrids exhibit reduced cytotoxicity toward 3T3 fibroblasts.