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Polymeric Biomaterials for Stem Cell Bioengineering
Author(s) -
Prewitz Marina,
Seib Friedrich Philipp,
Pompe Tilo,
Werner Carsten
Publication year - 2012
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201200382
Subject(s) - reprogramming , stem cell , induced pluripotent stem cell , mesenchymal stem cell , tissue engineering , nanotechnology , regenerative medicine , materials science , microbiology and biotechnology , cell , biology , biomedical engineering , medicine , embryonic stem cell , biochemistry , gene
This review covers the application of polymeric materials in stem cell bioengineering. Main emphasis is directed towards current material design concepts that mimic distinct exogenous signals of the stem cell microenvironment. Progress within the field of stem cell‐specific biomaterials will be discussed, focusing on pluripotent, hematopoietic, mesenchymal and neural stem cells. The future role of biomaterials will be outlined with possible applications for cell reprogramming and engineering cancer cell microenvironments.