Premium
Thermoresponsive Macroporous Scaffolds Prepared by Emulsion Templating
Author(s) -
Zhou Shengzhong,
Bismarck Alexander,
Steinke Joachim H. G.
Publication year - 2012
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201200336
Subject(s) - self healing hydrogels , polymer , monomer , emulsion , materials science , chemical engineering , aqueous solution , polymerization , porosity , polymer chemistry , aqueous two phase system , chemistry , organic chemistry , composite material , engineering
A versatile method to prepare non‐covalently crosslinked polyHIPEs hydrogels from oil‐in‐water high internal phase emulsions (HIPEs) whose aqueous phase contained thermo‐responsive linear polymers is described. The interconnected pore structure of the polyHIPEs is maintained by reversible physical aggregation of thermo‐responsive polymer chains in an aqueous environment. This method to prepare interconnected porous hydrogels using a thermal trigger in the guise of thermo‐responsive polymers by emulsion templating requires no chemical reaction during solidification of the template. This particular feature could provide a safer route to injectable scaffolds as issues of polymerisation/crosslinking chemistry and residual initiator fragments or monomers do not arise