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Combining Modular Ligation and Supramolecular Self‐Assembly for the Construction of Star‐Shaped Macromolecules
Author(s) -
Altintas Ozcan,
Muller Thierry,
Lejeune Elise,
Plietzsch Oliver,
Bräse Stefan,
BarnerKowollik Christopher
Publication year - 2012
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201200019
Subject(s) - copolymer , polymer chemistry , macromolecule , supramolecular chemistry , polymer , materials science , chemistry , crystallography , organic chemistry , crystal structure , biochemistry
A well‐defined random copolymer of styrene (S) and chloromethylstyrene (CMS) featuring lateral chlorine moieties with an alkyne terminal group is prepared (P(S‐ co ‐CMS), $\overline{M}_{\rm n}$ = 5500 Da, PDI = 1.13). The chloromethyl groups are converted into Hamilton wedge (HW) entities (P(S‐ co ‐HWS), $\overline{M}_{\rm n}$ = 6200 Da, PDI = 1.13). The P(S‐ co ‐HWS) polymer is subsequently ligated with tetrakis(4‐azidophenyl)methane to give HW‐functional star‐shaped macromolecules (P(S‐ co ‐HWS)) 4 , $\overline{M}_{\rm n}$ = 25 100 Da, PDI = 1.08). Supramolecular star‐shaped copolymers are then prepared via self‐assembly between the HW‐functionalized four‐arm star‐shaped macromolecules ( P(S‐ co ‐HW )) 4 and cyanuric acid (CA) end‐functionalized PS (PS–CA, $\overline{M}_{\rm n}$ = 3700 Da, PDI = 1.04), CA end‐functionalized poly(methyl methacrylate) (PMMA–CA, $\overline{M}_{\rm n}$ = 8500 Da, PDI = 1.13) and CA end‐functionalized polyethylene glycol (PEG–CA, $\overline{M}_{\rm n}$ = 1700 Da, PDI = 1.05). The self‐assembly is monitored by 1 H NMR spectroscopy and light scattering analyses.