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Surface‐Modifiable Free‐Floating Films Formed by Multiway Connection of Collagen‐Like Triple‐Helical Peptides
Author(s) -
Matsui Shunsuke,
Yamazaki Chisato M.,
Koide Takaki
Publication year - 2012
Publication title -
macromolecular rapid communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.348
H-Index - 154
eISSN - 1521-3927
pISSN - 1022-1336
DOI - 10.1002/marc.201100764
Subject(s) - avidin , biotinylation , triple helix , biotin , materials science , biosensor , peptide , buffer (optical fiber) , surface modification , connection (principal bundle) , nanotechnology , chemistry , computer science , stereochemistry , mathematics , biochemistry , telecommunications , geometry
Square‐millimeter‐sized free‐floating translucent films are formed in physiological buffer by multiway connections between biotinylated collagen‐like triple‐helical peptides and avidin. Although the compositions of the films are almost constant, regardless of the ratios of the components loaded, their thicknesses can be controlled by the concentrations of the components. The film surfaces can be further modified by taking advantage of exposed biotin (or avidin) functionalities. The self‐assembled films could serve as novel materials in biomedical and biosensing applications.